Shibuya: Setting the Aseptic Standard for Beverage and Pharmaceutical Filling
Dual-Industry Leadership in Aseptic Technology
Shibuya is recognized as one of only two companies leading the way in aseptic manufacturing solutions for both the beverage and pharmaceutical sectors, delivering unmatched standards for safety, quality, and efficiency.
Proven Expertise in Beverage Aseptic Filling
Aseptic beverage solutions from Shibuya are designed for minimal thermal impact, greater bottle design flexibility, and PET bottle lightweighting, all while meeting consumer demands for natural, healthy ingredients and sustainable packaging. These systems fill a diverse array of bottle types, including PET & HDPE, and support automatic changeover and high throughput, allowing beverage manufacturers to achieve maximum uptime and operational effectiveness. Shibuya has installed over 250 aseptic filling systems worldwide for top brands, with not a single product recall recorded due to their equipment.
Shibuya’s innovative dry aseptic technology uses hydrogen peroxide (H₂O₂) vapor for bottle decontamination, proven effective for the most sensitive (low-acid) beverage types, with residuals below 0.5 ppm, meeting the USA FDA’s stringent safety requirements. This process reduces operational costs, as it eliminates the need for water rinsing and allows use of lightweight bottles, ultimately lowering total cost of ownership compared to hot fill systems.
These lines are purpose-built for operational excellence:
- Capable of handling container sizes from 60–3,800ml at up to 1,200 bottles per minute (72,000 bph)
- Precision net weight filling and 100% servo-controlled capping for absolute accuracy
- Advanced isolation and sealing designs maintain sterility for over 200 hours of continuous production without intermediate CIP/SIP interruption, setting industry benchmarks for uptime and system integrity
- Full traceability with real-time quality monitoring for every fill and cap operation
Shibuya also offers electron beam (EB) and peracetic acid (PAA) aseptic/ESL beverage filling systems, providing tailored solutions for beverage characteristics and regulatory demands.
Pharmaceutical Filling and Packaging Excellence
Shibuya’s aseptic systems also support pharmaceutical production, offering isolators and cleanroom solutions for critical products such as injection solutions, solid medications, and transfusion bags. Their precision engineering ensures strict quality controls for all pharmaceutical needs and also lends itself to other facets including cell culture processes and the advanced needs of regenerative medicine which Shibuya is a market leader.
Shibuya’s pharmaceutical systems feature isolators and filling lines designed to meet cGMP and ISO Class 5 environments, with hydrogen peroxide decontamination for rapid, effective cleaning. Thanks to in-house design and manufacturing of both isolators and decontamination units, Shibuya offers highly customizable, integrated lines for sterile production, including vial, ampoule, syringe, ophthalmic, bag and powder filling. All these systems support electronic data capture for every unit filled, delivering total traceability.
Shibuya’s close partnership with leading medical researchers has yielded innovations in the regenerative medicine industry such as automated bio 3D printers used in organoid and tissue engineering, demonstrating their unique ability to engineer bespoke aseptic automation for next-generation pharmaceuticals.
Innovation That Makes a Difference
What differentiates Shibuya is not just the scope of industries served but an unwavering commitment to innovation, bespoke engineering, and attentive customer partnership. Each aseptic filling solution is designed and refined with the goal of minimizing downtime, reducing ownership costs, and enhancing system efficiency for clients. Tool-less changeovers, modular platforms, and streamlined architecture reduce cleaning and maintenance time, keeping multi-SKU facilities running at maximum uptime even in demanding environments like dairy, plant-based beverages, or high-particulate products.
Why Global Producers Choose Shibuya
By remaining at the forefront of aseptic technology for both beverages and pharmaceuticals, Shibuya delivers the safety, flexibility, and operational performance that global producers require to stay ahead in today’s evolving markets. With more than 1,200 aseptic units for beverage and pharma delivered worldwide and a track record of zero equipment-related recalls, Shibuya stands as the premier partner for producers seeking uncompromising product safety, sustainability, and performance.